Prognostic Factors for Survival or Severity After COVID-19 Infection in Cancer Patients: A Systematic Review and Meta-Analysis

Background and Objectives: Cancer organizations worldwide have recently released care guidelines for cancer patients with coronavirus disease 2019 (COVID-19). Several studies reported higher mortality rates in COVID-19. However, drawing robust conclusions remains challenging due to a lack of research on clinical prognostic factors this patient group.Methods: A comprehensive literature search was conducted using the PubMed, Embase, Cochrane databases. We searched keywords following combination: (“COVID-19” or “coronavirus” “wuhan virus”) (“cancer”). The performed August 1, 2020, only papers written English were included study. collected data from 3,215 COVID-19 16 analyzed overall after infection compared controls, as well severity infection. encompassed demographics, comorbidities, symptoms, treatment within 4 weeks diagnosis, infection.Results: This meta-analysis evaluated related infected First, 15 data; 663 died among total people, resulting combined rate 21%. Second, poor identified: male sex, older age (≥65 years), respiratory symptoms (e.g., cough dyspnea), other comorbidities cardiovascular disease, hypertension, chronic obstructive pulmonary disease).Conclusion: can reach about 20%.